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Article

Effects of mutating putative two-component systems on biofilm formation by Streptococcus mutans UA159.

FEMS microbiology letters - 18 Dec 2001

Bhagwat S P, Nary J, Burne R A

Abstract excerpt

Streptococcus mutans has at least six pairs of open reading frames that are homologous to bacterial two-component regulatory systems. Putative response regulators from five out of six of these pairs were successfully mutated by insertion of a kanamycin resistance marker and the effects of inactivation of the genes on the ability of the cells to form biofilms in an in vitro model were assessed. Disruption of the...

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Identifiers

PMID: 11750807
DOI: 10.1111/j.1574-6968.2001.tb10952.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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