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Article

Functional genomics approach to identifying genes required for biofilm development by Streptococcus mutans.

Applied and environmental microbiology - 1 Mar 2002

Wen Zezhang T, Burne Robert A

Abstract excerpt

Streptococcus mutans, the primary etiological agent of human dental caries, is an obligate biofilm-forming bacterium. The goals of this study were to identify the gene(s) required for biofilm formation by this organism and to elucidate the role(s) that some of the known global regulators of gene expression play in controlling biofilm formation. In S. mutans UA159, the brpA gene (for biofilm regulatory protein)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11872468
DOI: 10.1128/AEM.68.3.1196-1203.2002
PMCID: PMC123778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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