Article
SMU.940 regulates dextran-dependent aggregation and biofilm formation in Streptococcus mutans.
Molecular oral microbiology - 1 Feb 2018
Senpuku Hidenobu, Yonezawa Hideo, Yoneda Saori, Suzuki Itaru, Nagasawa Ryo, Narisawa Naoki
Abstract excerpt
The oral bacterium Streptococcus mutans is the principal agent in the development of dental caries. Biofilm formation by S. mutans requires bacterial attachment, aggregation, and glucan formation on the tooth surface under sucrose supplementation conditions. Our previous microarray analysis of clinical strains identified 74 genes in S. mutans that were related to biofilm morphology; however, the roles of almost...
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