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A genome-wide study of two-component signal transduction systems in eight newly sequenced mutans streptococci strains

4 Apr 2012

Abstract excerpt

BACKGROUND: Mutans streptococci are a group of gram-positive bacteria including the primary cariogenic dental pathogen Streptococcus mutans and closely related species. Two component systems (TCSs) composed of a signal sensing histidine kinase (HK) and a response regulator (RR) play key roles in pathogenicity, but have not been comparatively studied for these oral bacterial pathogens. RESULTS: HKs and RRs of 8...

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PMID: 22475007
DOI: 10.1186/1471-2164-13-128

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