Article
Strain-specific complementation between NRIF1 and NRIF2, two zinc finger proteins sharing structural and biochemical properties.
Gene - 27 Dec 2001
Benzel I, Barde Y A, Casademunt E
Abstract excerpt
The zinc finger protein NRIF (neurotrophin receptor interacting factor) was originally identified by virtue of its interaction with the neurotrophin receptor p75NTR and its participation in embryonic apoptosis. Targeted deletion of the nrif gene in mice is embryonically lethal in the C57BL6 genetic background, where it blocks cell cycle progression, but not in the Sv129 strain. We have now identified a second,...
Topics
- Amino Acid Sequence
- Animals
- Carrier Proteins
- Cell Cycle
- Cloning, Molecular
- DNA, Complementary
- DNA-Binding Proteins
- Gene Expression
- Genetic Complementation Test
- Intracellular Signaling Peptides and Proteins
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL