Article
Short tandem repeat polymorphism linkage to the androgen receptor gene in prostate carcinoma.
Cancer - 15 Nov 2001
Riley D E, Krieger J N
Abstract excerpt
BACKGROUND: Due to high polymorphism, common sequences, and ubiquitous presence, short tandem repeats (STRs) may enhance genomic typing to determine prostate carcinoma (CaP) predisposition. The human phosphoglycerate kinase (PGK1) gene is located within Xq11-Xq13, a region implicated in familial prostate carcinoma, androgen insensitivity, perineal hypospadias, and other genitourinary abnormalities. The PGK1 STR...
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