Article
Association of androgen receptor, prostate-specific antigen, and CYP19 gene polymorphisms with prostate carcinoma and benign prostatic hyperplasia in a north Indian population.
Genetic testing and molecular biomarkers - 1 Aug 2012
Soni Abha, Bansal Anju, Mishra Ashwani Kumar, Batra Jyotsna, Singh Laishram Chandreshwor, Chakraborty Anurupa, Yadav Dhirendra Singh, Mohanty Nayan K, Saxena Sunita
Abstract excerpt
The genes involved in androgen pathway and metabolism have been reported to contribute considerably to prostate carcinoma (CaP) risk. The present study investigated the association of androgen receptor (AR), prostate-specific antigen (PSA or KLK3), and cytochrome P450 (CYP19) gene polymorphisms in CaP (n=105) and benign prostatic hyperplasia (BPH) (n=120) in comparison to normal healthy controls (n=106) in an...
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