Article
Polymorphic forms of prostate specific antigen and their interaction with androgen receptor trinucleotide repeats in prostate cancer.
The Prostate - 1 Jun 2005
Binnie Margaret C, Alexander Freda E, Heald Charlotte, Habib Fouad K
Abstract excerpt
BACKGROUND: Recent data has suggested that polymorphisms in the prostate specific antigen (PSA) may increase prostate cancer (PC) risk. The PSA gene contains a G/A substitution in the androgen response element (ARE) 1 region. The androgen receptor (AR) gene has polymorphic regions containing variable length glutamine and glycine repeats and these are believed to be associated with PC risk. The effect on PC risks...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
