Article
A triad of serum response factor and the GATA and NK families governs the transcription of smooth and cardiac muscle genes.
The Journal of biological chemistry - 1 Mar 2002
Nishida Wataru, Nakamura Mako, Mori Syunsuke, Takahashi Masanori, Ohkawa Yasuyuki, Tadokoro Satoko, Yoshida Kenji, Hiwada Kunio, Hayashi Ken'ichiro, Sobue Kenji
Abstract excerpt
Serum response factor and the (CC(A/T)(6)GG) (CArG) box interact to promote the transcription of c-fos and muscle genes; this tissue-specific activity may require co-regulators for serum response factor. The alpha(1) integrin promoter contains two cis-elements besides the CArG box: a TAAT sequence, a consensus binding site for homeoproteins, and a GATA-binding box. As a candidate TAAT-binding factor, we cloned an...
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