Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of acamprosate on sensitization to the locomotor-stimulant effects of alcohol in mice selectively bred for high and low alcohol preference.

Behavioural pharmacology - 1 Nov 2001

Chester J A, Grahame N J, Li T K, Lumeng L, Froehlich J C

Abstract excerpt

Sensitization to the locomotor-stimulant effects of drugs is thought to play an important role in the development of drug-seeking behaviour. We hypothesized that the ability of acamprosate to reduce alcohol relapse rates in recovering alcoholics, and alcohol consumption in rodents, may be related to its ability to reduce sensitization to the locomotor-stimulant effects of alcohol. The purpose of the present study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Drug Interactions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ethanol

Share to Mice, Inbred Strains

Share to Motor Activity

Share to Selection, Genetic

Share to Taurine

Source

Identifiers

PMID: 11742148
DOI: 10.1097/00008877-200111000-00015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of acamprosate on sensitization to the locomotor-stimulant effects of alcohol in mice selectively bred for high and low alcohol preference.PMID 11742148Read ↗

Role of genotype in the development of locomotor sensitization to alcohol in adult and adolescent mice: comparison of the DBA/2J and C57BL/6J inbred mouse strains.Semantic proximity Read ↗

Behavior genetics of drug sensitization.Semantic proximity Read ↗

Accentuating effects of nicotine on ethanol response in mice with high genetic predisposition to ethanol-induced locomotor stimulation.Semantic proximity Read ↗

Selective breeding for magnitude of methamphetamine-induced sensitization alters methamphetamine consumption.Semantic proximity Read ↗

Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity.Semantic proximity Read ↗

alpha(2A)-Adrenoceptors regulate d-amphetamine-induced hyperactivity and behavioural sensitization in mice.Semantic proximity Read ↗

Evidence of long-term expression of behavioral sensitization to both cocaine and ethanol in dopamine transporter knockout mice.Semantic proximity Read ↗

The psychogenetically selected Roman high- and low-avoidance rat lines: a model to study the individual vulnerability to drug addiction.Semantic proximity Read ↗

Methamphetamine-induced locomotor changes are dependent on age, dose and genotype.Semantic proximity Read ↗

Bidirectional selective breeding for ethanol effects on locomotor activity: characterization of FAST and SLOW mice through selection generation 35.Semantic proximity Read ↗

Basal anxiety negatively correlates with vulnerability to ethanol-induced behavioral sensitization in DBA/2J mice: modulation by diazepam.Semantic proximity Read ↗

The psychogenetically selected Roman rat lines differ in the susceptibility to develop amphetamine sensitization.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.