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Article

Phosphorylation regulates the nucleocytoplasmic distribution of kinase suppressor of Ras.

The Journal of biological chemistry - 15 Feb 2002

Brennan Jennifer A, Volle Deanna J, Chaika Oleg V, Lewis Robert E

Abstract excerpt

KSR (kinase suppressor of Ras) has been proposed as a molecular scaffold regulating the Raf/MEK/ERK kinase cascade. KSR is phosphorylated on multiple phosphorylation sites by associated kinases. To identify potential mechanisms used by KSR to regulate ERK activation, green fluorescent protein was fused to intact and mutated KSR constructs lacking specific phosphorylation sites, and the subcellular distribution of...

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Identifiers

PMID: 11741955
DOI: 10.1074/jbc.M109875200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Phosphorylation regulates the nucleocytoplasmic distribution of kinase suppressor of Ras.PMID 11741955Read ↗

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