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Article

Multiple Rho proteins regulate the subcellular targeting of PAK5.

Biochemical and biophysical research communications - 15 Dec 2006

Wu Xiaochong, Frost Jeffrey A

Abstract excerpt

We investigated the regulatory mechanisms controlling the subcellular localization of p21-activated kinase 5 (PAK5) and found that the Cdc42/Rac interactive binding (CRIB) domain within PAK5 is critical for proper targeting within the cell. We also observed that PAK5 interacts with RhoD and RhoH in addition to Cdc42, and that interaction with RhoD targets PAK5 to subcellular locations that are distinct from those...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17064668
DOI: 10.1016/j.bbrc.2006.09.172

Genes

PAK5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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