Article
Cell type-specific and tyrosine phosphorylation-independent nuclear presence of STAT1 and STAT3.
Experimental cell research - 1 Jan 2002
Meyer Thomas, Gavenis Karsten, Vinkemeier Uwe
Abstract excerpt
Tyrosine phosphorylation in response to cytokine stimulation of cells is believed to be required for the nuclear translocation of cytoplasmic STAT proteins (signal transducers and activators of transcription). In this study we examined the nucleocytoplasmic distribution of STAT1 and STAT3 in transformed cell lines and primary cells prior to stimulation with cytokines. It was found that both STAT1 and STAT3 are...
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