Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotyping of thrombotic risk factors by MALDI-TOF mass spectrometry.

Clinical biochemistry - 1 Oct 2001

Humeny A, Bonk T, Berkholz A, Wildt L, Becker C M

Abstract excerpt

OBJECTIVES: Individual risk of thrombotic disease is highly associated with allelic sequence variations in the blood clotting factor V (F5) and factor II (F2) genes. The polymorphism (G1691A) in F5 causing the amino acid substitution R506Q and a genetic variation in the 3' untranslated region of F2 (G20210A) are highly prevalent in the Caucasian population. These findings raise the need for an efficient,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Factor V
Share to Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Prothrombin

Share to Risk Factors

Share to Sequence Analysis, DNA

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Share to Thrombosis

Source

Identifiers

PMID: 11738388
DOI: 10.1016/s0009-9120(01)00264-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotyping of thrombotic risk factors by MALDI-TOF mass spectrometry.PMID 11738388Read ↗

Rapid multiplexed genotyping for hereditary thrombophilia by SELDI-TOF mass spectrometry.Semantic proximity Read ↗

Prevalence of Rare F5 Variants in General Population From Bosnia and HerzegovinaSemantic proximity Read ↗

Prevalence of rare F5 variants in general population from Bosnia and Herzegovina.Semantic proximity Read ↗

Factor V Leiden and factor V R2 allele: high-throughput analysis and association with venous thromboembolism.Semantic proximity Read ↗

A genetic risk factor for thrombophilia in a Han Chinese family.Semantic proximity Read ↗

Plasma levels of complement components C5 and C9 are associated with thrombin generation.Semantic proximity Read ↗

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for genotyping of human platelet-specific antigens.Semantic proximity Read ↗

Congenital factor V deficiency from compound heterozygous mutations with a novel variant c.2426del (p.Pro809Hisfs*2) in the F5 gene: A case report.Semantic proximity Read ↗

Thrombin generation as an intermediate phenotype for venous thrombosis.Semantic proximity Read ↗

Pyrosequencing analysis of thrombosis-associated risk markers.Semantic proximity Read ↗

Novel fibrinogen mutations (Aα17Gly→Cys and Aα381Ser→Phe) occurring with a 312Thr→Ala polymorphism: allelic phase assigned by direct mass measurement.Semantic proximity Read ↗

[Identification of Genetic Markers of Predisposition to Thrombogenic Diseases by Minisequencing Analysis: Reagent Set "SNP2-TMG"].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.