Article
Prevalence of rare F5 variants in general population from Bosnia and Herzegovina.
Molecular biology reports - 1 Jun 2021
Ašić Adna, Salazar Ramona, Storm Niels, Doğan Serkan, Höppner Wolfgang, Marjanović Damir, Primorac Dragan
Abstract excerpt
Human gene F5, encoding coagulation factor V, was previously reported to be highly polymorphic. Apart from FV Leiden, several other rare variants have been detected in clinical practice and associated with thrombotic events, especially in cases when patient's phenotype and FV Leiden genotype were not in agreement. In this study, the prevalence of 17 rare F5 variants has been studied on a sample of 130 healthy...
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