Article
Mutations in dihydropteroate synthase gene of Pneumocystis carinii in HIV patients with Pneumocystis carinii pneumonia.
International journal of antimicrobial agents - 1 Dec 2001
Visconti E, Ortona E, Mencarini P, Margutti P, Marinaci S, Zolfo M, Siracusano A, Tamburrini E
Abstract excerpt
The purpose of this study was to determine whether dihydropteroate synthase gene (DHPS) mutations were associated with the failure of sulpha/sulphone drugs used as prophylaxis agents in HIV infected patients. Results suggested that DHPS mutations were significantly associated with failure of anti...
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