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Article

Quantifying viral propagation in vitro: toward a method for characterization of complex phenotypes.

Biotechnology progress - 1 Jan 2000

Duca K A, Lam V, Keren I, Endler E E, Letchworth G J, Novella I S, Yin J

Abstract excerpt

For a eukaryotic virus to successfully infect and propagate in cultured cells several events must occur: the virion must identify and bind to its cellular receptor, become internalized, uncoat, synthesize viral proteins, replicate its genome, assemble progeny virions, and exit the host cell. While these events are taking place, intrinsic host defenses activate in order to defeat the virus, e.g., activation of the...

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PMID: 11735454
DOI: 10.1021/bp010115m

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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