Article
Plaques Formed by Mutagenized Viral Populations Have Elevated Coinfection Frequencies.
mBio - 14 Mar 2017
Aguilera Elizabeth R, Erickson Andrea K, Jesudhasan Palmy R, Robinson Christopher M, Pfeiffer Julie K
Abstract excerpt
The plaque assay is a common technique used to measure virus concentrations and is based upon the principle that each plaque represents a single infectious unit. As such, the number of plaques is expected to correlate linearly with the virus dilution plated, and each plaque should be formed by a single founder virus. Here, we examined whether more than one virus can contribute to plaque formation. By using...
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