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Spatial-Temporal Patterns of Viral Amplification and Interference Initiated by a Single Infected Cell

9 Jun 2016

Abstract excerpt

UNLABELLED: When viruses infect their host cells, they can make defective virus-like particles along with intact virus. Cells coinfected with virus and defective particles often exhibit interference with virus growth caused by the competition for resources by defective genomes. Recent reports of the coexistence and cotransmission of such defective interfering particles (DIPs) in vivo, across epidemiological...

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PMID: 27279621
DOI: 10.1128/jvi.00807-16

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