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The LIM domain gene <i>LMO4</i> inhibits differentiation of mammary epithelial cells <i>in vitro</i> and is overexpressed in breast cancer

4 Dec 2001

Abstract excerpt

LMO4 belongs to a family of LIM-only transcriptional regulators, the first two members of which are oncoproteins in acute T cell leukemia. We have explored a role for LMO4, initially described as a human breast tumor autoantigen, in developing mammary epithelium and breast oncogenesis. Lmo4 was expressed predominantly in the lobuloalveoli of the mammary gland during pregnancy. Consistent with a role in...

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PMID: 11734645
DOI: 10.1073/pnas.251547698

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The LIM domain gene <i>LMO4</i> inhibits differentiation of mammary epithelial cells <i>in vitro</i> and is overexpressed in breast cancerPMID 11734645Read ↗

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