Article
Accurate chromatin organization of the mouse mammary tumor virus promoter determines the nature of the synergism between transcription factors.
The Journal of biological chemistry - 15 Feb 2002
Prado Felix, Koop Ronald, Beato Miguel
Abstract excerpt
The mechanism underlying the synergism between transcription factors in eukaryotic gene expression is not fully understood. In minichromosomes assembled in vitro the synergism between steroid hormone receptors (SHRs) and nuclear factor 1 (NF1) on the mouse mammary tumor virus (MMTV) promoter does not require the proline-rich transactivation domain (PRD) of NF1. Here we show that similar results are obtained in...
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