Article
Trimming, weighting, and grouping SNPs in human case-control association studies.
Genome research - 1 Dec 2001
Hoh J, Wille A, Ott J
Abstract excerpt
The search for genes underlying complex traits has been difficult and often disappointing. The main reason for these difficulties is that several genes, each with rather small effect, might be interacting to produce the trait. Therefore, we must search the whole genome for a good chance to find these genes. Doing this with tens of thousands of SNP markers, however, greatly increases the overall probability of...
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