Article
Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein.
Immunity - 1 Nov 2001
Boackle S A, Holers V M, Chen X, Szakonyi G, Karp D R, Wakeland E K, Morel L
Abstract excerpt
The major murine systemic lupus erythematosus (SLE) susceptibility locus, Sle1, corresponds to three loci independently affecting loss of tolerance to chromatin in the NZM2410 mouse. The congenic interval corresponding to Sle1c contains Cr2, which encodes complement receptors 1 and 2 (CR1/CR2, CD...
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