Article
Release of U18 snoRNA from its host intron requires interaction of Nop1p with the Rnt1p endonuclease.
The EMBO journal - 3 Dec 2001
Giorgi C, Fatica A, Nagel R, Bozzoni I
Abstract excerpt
An external stem, essential for the release of small nucleolar RNAs (snoRNAs) from their pre-mRNAs, flanks the majority of yeast intron-encoded snoRNAs. Even if this stem is not a canonical Rnt1p substrate, several experiments have indicated that the Rnt1p endonuclease is required for snoRNA processing. To identify the factors necessary for processing of intron-encoded snoRNAs, we have raised in vitro extracts...
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