Article
Quantitative analysis of snoRNA association with pre-ribosomes and release of snR30 by Rok1 helicase.
EMBO reports - 1 Dec 2008
Bohnsack Markus T, Kos Martin, Tollervey David
Abstract excerpt
In yeast, three small nucleolar RNAs (snoRNAs) are essential for the processing of pre-ribosomal RNA--U3, U14 and snR30--whereas 72 non-essential snoRNAs direct site-specific modification of pre-rRNA. We applied a quantitative screen for alterations in the pre-ribosome association to all 75 yeast snoRNAs in strains depleted of eight putative helicases implicated in 40S subunit synthesis. For the...
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