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Article

Involvement of Fc gamma receptor polymorphism in the therapeutic response of idiopathic thrombocytopenic purpura.

British journal of haematology - 1 Oct 2001

Fujimoto T T, Inoue M, Shimomura T, Fujimura K

Abstract excerpt

Clearance of autoantibody-sensitized platelets through Fc gamma receptors on phagocytic cells is one of the main mechanisms of thrombocytopenia in idiopathic thrombocytopenic purpura (ITP). We examined the Fc gamma RIIA-131R/H and Fc gamma RIIIA-158V/F polymorphisms in 104 adult chronic ITP patients, and in 59 healthy control subjects using polymerase chain reaction-based allele-specific restriction analysis. The...

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Share to Autoantibodies
Share to Patient Selection
Share to Platelet Glycoprotein GPIb-IX Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Platelet Glycoprotein GPIIb-IIIa Complex

Share to Purpura, Thrombocytopenic, Idiopathic

Share to Receptors, IgG

Share to Remission Induction

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 11722422
DOI: 10.1046/j.1365-2141.2001.03109.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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