Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of Fc gamma receptor IIa and IIIa gene polymorphisms on the therapeutic response of rituximab in Egyptian adult immune thrombocytopenic purpura.

Hematology (Amsterdam, Netherlands) - 1 Apr 2018

Ellithy Hend N, Ahmed Salwa H, Shahin Gehan H, Matter Mervat M, Talatt Mohamed

Abstract excerpt

Background In chronic immune thrombocytopenic purpura (ITP), rituximab removes the harmful autoantibodies through antibody-dependent cellular cytotoxicity. The response to rituximab in ITP is variable; the effectiveness of rituximab is influenced by the process of activation of effector fragment C gamma receptors (FcγRs). Genetic factors may affect the response to rituximab. Objectives The influence of FcγRIIa...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents, Immunological
Share to Platelet Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Purpura, Thrombocytopenic, Idiopathic

Share to Receptors, IgG

Share to Rituximab

Share to Treatment Outcome

Share to Young Adult

Source

Identifiers

PMID: 28856973
DOI: 10.1080/10245332.2017.1371479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of Fc gamma receptor IIa and IIIa gene polymorphisms on the therapeutic response of rituximab in Egyptian adult immune thrombocytopenic purpura.PMID 28856973Read ↗

FcγRIIa and FcγRIIIa genetic polymorphisms in a group of pediatric immune thrombocytopenic purpura in Egypt.Semantic proximity Read ↗

[Polymorphisms of FcγRIIA, FcγRIIIA and FcγRIIB in patients with immune thrombocytopenia and their clinical significance].Semantic proximity Read ↗

FC gamma receptor polymorphisms in patients with immune thrombocytopenia.Semantic proximity Read ↗

FcγRIIIa polymorphism in pediatric immune thrombocytopenia: impact on clinical course and outcomeSemantic proximity Read ↗

Involvement of Fc gamma receptor polymorphism in the therapeutic response of idiopathic thrombocytopenic purpura.Semantic proximity Read ↗

Fcγ receptor gene polymorphisms in childhood immune thrombocytopenic purpura.Semantic proximity Read ↗

Association between gene polymorphisms and clinical features in idiopathic thrombocytopenic purpura patients.Semantic proximity Read ↗

Platelet-associated antibodies, cellular immunity and FCGR3a genotype influence the response to rituximab in immune thrombocytopenia.Semantic proximity Read ↗

Correlation of FcγRIIIa Polymorphisms to the Response of Rituximab in Thai Patients with Diffuse Large B-Cell Lymphoma.Semantic proximity Read ↗

Association between functional FCGR3A F158V and FCGR2A R131H polymorphisms and responsiveness to rituximab in patients with autoimmune diseases: a meta-analysis.Semantic proximity Read ↗

FcγRIIa and FcγRIIIa polymorphisms in childhood primary immune thrombocytopenia: implications for disease pathogenesis and outcome.Semantic proximity Read ↗

FcgammaRIIa polymorphism and clinical response to rituximab in non-Hodgkin lymphoma patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.