Article
Genetic epidemiology: systemic lupus erythematosus.
Arthritis research - 1 Jan 2001
Ahmad Y A, Bruce I N
Abstract excerpt
Systemic lupus erythematosus is the prototype multisystem autoimmune disease. A strong genetic component of susceptibility to the disease is well established. Studies of murine models of systemic lupus erythematosus have shown complex genetic interactions that influence both susceptibility and phenotypic expression. These models strongly suggest that several defects in similar pathways, e.g. clearance of immune...
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