Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of putative anticancer targets in familial adenomatous polyposis and its association with the APC mutation status.

International journal of oncology - 1 Dec 2001

Humar B, D'Orazio D, Albrecht C, Bauerfeind P, Muller H, Dobbie Z, Bendik I

Abstract excerpt

Several substances interfering with colorectal carcinogenesis may reduce or prevent adenoma formation in familial adenomatous polyposis (FAP), an inherited predisposition to colorectal cancer. This study determined the expression of genes coding for putative anticancer targets (COX-2, iNOS, MMP-7...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli
Share to Adenomatous Polyposis Coli Protein
Share to Anticarcinogenic Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Gene Expression

Share to Genes, APC

Share to Neoplasm Proteins

Share to RNA, Messenger

Source

Identifiers

PMID: 11713587
DOI: 10.3892/ijo.19.6.1179

Genes

FAP
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11713587-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of putative anticancer targets in familial adenomatous polyposis and its association with the APC mutation status.PMID 11713587Read ↗

Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention.Semantic proximity Read ↗

The Adenomatous Polyposis Coli Tumor Suppressor Gene Regulates Expression of Cyclooxygenase-2 by a Mechanism That Involves Retinoic AcidSemantic proximity Read ↗

Gene Expression Profile of Colon Mucosa after Cytotoxic Insult in wt and Apc-Mutated Pirc Rats: Possible Relation to Resistance to Apoptosis during Carcinogenesis.Semantic proximity Read ↗

Colon fibroblasts from Pirc rats (F344/NTac-Apcam1137 ) exhibit a proliferative and inflammatory phenotype that could support early stages of colon carcinogenesis.Semantic proximity Read ↗

Alteration of Gene Expression in Macroscopically Normal Colonic Mucosa from Individuals with a Family History of Sporadic Colon CancerSemantic proximity Read ↗

PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States).Semantic proximity Read ↗

Gene mutations and altered gene expression in azoxymethane-induced colon carcinogenesis in rodents.Semantic proximity Read ↗

PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo.Semantic proximity Read ↗

Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis.Semantic proximity Read ↗

Protective effect of nonsteroidal anti-inflammatory drugs on colorectal adenomas is modified by a polymorphism in peroxisome proliferator-activated receptor delta.Semantic proximity Read ↗

Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells.Semantic proximity Read ↗

Elevated protein kinase C betaII is an early promotive event in colon carcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.