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Article

Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells.

The Journal of biological chemistry - 10 Aug 2001

Gupta R A, Brockman J A, Sarraf P, Willson T M, DuBois R N

Abstract excerpt

Activation of the nuclear hormone peroxisome proliferator-activated receptor gamma (PPARgamma) inhibits cell growth and promotes differentiation in a broad spectrum of epithelial derived tumor cell lines. Here we utilized microarray technology to identify PPARgamma gene targets in intestinal epithelial cells. For each gene, the induction or repression was seen with two structurally distinct PPARgamma agonists,...

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Identifiers

PMID: 11397807
DOI: 10.1074/jbc.M103779200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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