Article
Structural and functional analysis of 5S rRNA in Saccharomyces cerevisiae.
Molecular genetics and genomics : MGG - 1 Oct 2005
Kiparisov Sergey, Petrov Alexey, Meskauskas Arturas, Sergiev Petr V, Dontsova Olga A, Dinman Jonathan D
Abstract excerpt
5S rRNA extends from the central protuberance of the large ribosomal subunit, through the A-site finger, and down to the GTPase-associated center. Here, we present a structure-function analysis of seven 5S rRNA alleles which are sufficient for viability in the yeast Saccharomyces cerevisiae when expressed in the absence of wild-type 5S rRNAs, and extend this analysis using a large bank of mutant alleles that show...
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