Article
Use of mutant RNAs in studies on yeast 5S rRNA structure and function.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Apr 1991
Nazar R N, Van Ryk D I, Lee Y, Guyer C D
Abstract excerpt
The expression of mutant yeast 5S rRNA genes in vivo is reviewed as a basis for further studies on the structure, function, and regulation of the ribosomal 5S rRNA. Specific base substitutions, insertions, or deletions can result in substantial structural changes which can be detected readily by gel electrophoresis, permitting the assay of mutant RNA synthesis and utilization. Furthermore, the use of high and low...
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