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Article

Amino acid sequences flanking polyglutamine stretches influence their potential for aggregate formation.

Neuroreport - 29 Oct 2001

Nozaki K, Onodera O, Takano H, Tsuji S

Abstract excerpt

Expanded polyglutamine stretches have been shown to form aggregates and to be toxic to cells. In this study, we hypothesized that amino acid sequences flanking the polyglutamine stretches influence the aggregate formation potential of these stretches. Green fluorescent protein (GFP) fusion proteins containing glutamine repeats of various lengths and a fixed number of flanking amino acids of ataxin-2, huntingtin,...

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Identifiers

PMID: 11711886
DOI: 10.1097/00001756-200110290-00042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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