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Article

Glutamine repeats and inherited neurodegenerative diseases: molecular aspects.

Current opinion in structural biology - 1 Dec 1996

Perutz M F

Abstract excerpt

Several dominantly inherited, late onset, neurodegenerative diseases are due to expansion of CAG repeats, leading to expansion of glutamine repeats in the affected proteins. These proteins are of very different sizes and, with one exception, show no sequence homology to known proteins or to each...

Topics

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Genetic Diseases, Inborn
Glutamine
Models, Molecular
Mutation
Nucleic Acid Conformation
Protein Structure, Secondary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombination, Genetic

Repetitive Sequences, Nucleic Acid

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Identifiers

PMID: 8994886
DOI: 10.1016/s0959-440x(96)80016-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8994886-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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