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Article

Genetic analyses of mutations contributing to fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae.

Antimicrobial agents and chemotherapy - 1 Dec 2001

Weigel L M, Anderson G J, Facklam R R, Tenover F C

Abstract excerpt

Twenty-one clinical isolates of Streptococcus pneumoniae showing reduced susceptibility or resistance to fluoroquinolones were characterized by serotype, antimicrobial susceptibility, and genetic analyses of the quinolone resistance-determining regions (QRDRs) of gyrA, gyrB, parC, and parE. Five strains were resistant to three or more classes of antimicrobial agents. In susceptibility profiles for gatifloxacin,...

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Identifiers

PMID: 11709333
DOI: 10.1128/AAC.45.12.3517-3523.2001
PMCID: PMC90862

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Source receipt: pubmed, retrieved 7 Sept 2026.

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