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Article

Cross-resistance, relatedness and allele analysis of fluoroquinolone-resistant US clinical isolates of Streptococcus pneumoniae (1998-2000).

The Journal of antimicrobial chemotherapy - 1 Aug 2003

Davies Todd A, Goldschmidt Raul, Pfleger Sharon, Loeloff Mike, Bush Karen, Sahm Daniel F, Evangelista Alan

Abstract excerpt

OBJECTIVES: To detect relatedness among 68 (0.5%) of 13 795 US clinical isolates of Streptococcus pneumoniae from the TRUST 3 (1998-1999) and TRUST 4 (1999-2000) surveillance studies that were resistant to levofloxacin (MIC > or = 8 mg/l). METHODS: All levofloxacin-resistant isolates were analysed by broth microdilution reference method for susceptibility to four fluoroquinolones, DNA sequencing of quinolone...

Topics

Adolescent
Adult
Alleles
Anti-Infective Agents
Cross Infection
Drug Resistance, Multiple, Bacterial
Female
Fluoroquinolones
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Serotyping

Streptococcus pneumoniae

United States

Source

Identifiers

PMID: 12837740
DOI: 10.1093/jac/dkg309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12837740-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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