Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors

10 Sept 2011

Abstract excerpt

A key challenge for the academic and biopharmaceutical communities is the rapid and scalable production of recombinant proteins for supporting downstream applications ranging from therapeutic trials to structural genomics efforts. Here, we describe a novel system for the production of recombinant mammalian proteins, including immune receptors, cytokines and antibodies, in a human cell line culture system, often...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Virus-based gene therapy research

Source

Identifiers

PMID: 21911364
DOI: 10.1093/nar/gkr706

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectorsPMID 21911364Read ↗

A nanobody-based strategy for rapid and scalable purification of native human protein complexesSemantic proximity Read ↗

Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteinsSemantic proximity Read ↗

Selectable high‐yield recombinant protein production in human cells using a GFP/YFP nanobody affinity supportSemantic proximity Read ↗

A simple, robust and highly efficient transient expression system for producing antibodiesSemantic proximity Read ↗

Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free MediaSemantic proximity Read ↗

An optimized retroviral toolbox for overexpression and genetic perturbation of primary lymphocytesSemantic proximity Read ↗

HEK293 Cell Line as a Platform to Produce Recombinant Proteins and Viral VectorsSemantic proximity Read ↗

Development of a CHO-Based Cell-Free Platform for Synthesis of Active Monoclonal AntibodiesSemantic proximity Read ↗

Recombinant Antibody Production Using a Dual-Promoter Single Plasmid SystemSemantic proximity Read ↗

A pipeline for the production of antibody fragments for structural studies using transient expression in HEK 293T cellsSemantic proximity Read ↗

Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteinsSemantic proximity Read ↗

Rapid high-throughput cloning and stable expression of antibodies in HEK293 cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.