Article
Novel retroviral vectors to facilitate expression screens in mammalian cells.
Nucleic acids research - 15 Dec 2002
Koh Eugene Y, Chen Tong, Daley George Q
Abstract excerpt
As tools for functional genomics, expression profiling and proteomics provide correlative data, while expression cloning screens can link genes directly to biological function. However, technical limitations of gene transfer, expression, and recovery of candidate genes have limited wider application of genome-wide expression screens. Here we describe the pEYK retroviral vectors, which maintain high titers and...
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