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Article

Proteomic and functional evidence for a P2X7 receptor signalling complex.

The EMBO journal - 15 Nov 2001

Kim M, Jiang L H, Wilson H L, North R A, Surprenant A

Abstract excerpt

P2X receptors are ATP-gated ion channels in the plasma membrane, but activation of the P2X7 receptor also leads to rapid cytoskeletal re-arrangements such as membrane blebbing. We identified 11 proteins in human embryonic kidney cells that interact with the rat P2X7 receptor, by affinity purification followed by mass spectroscopy and immunoblotting [laminin alpha3, integrin beta2, beta-actin, alpha-actinin,...

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Identifiers

PMID: 11707406
DOI: 10.1093/emboj/20.22.6347
PMCID: PMC125721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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