Article
Classification and characterization of human endogenous retroviruses; mosaic forms are common.
Retrovirology - 22 Jan 2016
Vargiu Laura, Rodriguez-Tomé Patricia, Sperber Göran O, Cadeddu Marta, Grandi Nicole, Blikstad Vidar, Tramontano Enzo, Blomberg Jonas
Abstract excerpt
BACKGROUND: Human endogenous retroviruses (HERVs) represent the inheritance of ancient germ-line cell infections by exogenous retroviruses and the subsequent transmission of the integrated proviruses to the descendants. ERVs have the same internal structure as exogenous retroviruses. While no replication-competent HERVs have been recognized, some retain up to three of four intact ORFs. HERVs have been classified...
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