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Endogenous retroviruses and human evolution.

1 Dec 2002

Abstract excerpt

Humans share about 99% of their genomic DNA with chimpanzees and bonobos; thus, the differences between these species are unlikely to be in gene content but could be caused by inherited changes in regulatory systems. Endogenous retroviruses (ERVs) comprise 5% of the human genome. The LTRs of ERVs contain many regulatory sequences, such as promoters, enhancers, polyadenylation signals and factor-binding sites....

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PMID: 18629260
DOI: 10.1002/cfg.216

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