Article
Identification of the sigB operon in Staphylococcus epidermidis: construction and characterization of a sigB deletion mutant.
Infection and immunity - 1 Dec 2001
Kies S, Otto M, Vuong C, Götz F
Abstract excerpt
The role of the alternative sigma factor sigma(B) in Staphylococcus epidermidis was investigated by the construction, complementation, and characterization of a sigB deletion mutant. Electrophoretic analyses confirmed a profound influence of sigma(B) on the expression of exoproteins and cytoplasmic proteins. Detailed investigation revealed reduced lipase and enhanced protease activity in the sigma(B) mutant....
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