Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel SigB(Q225P) mutation in Staphylococcus aureus retains virulence but promotes biofilm formation.

Emerging microbes & infections - 25 Apr 2018

Liu Hui, Shang Weilong, Hu Zhen, Zheng Ying, Yuan Jizhen, Hu Qiwen, Peng Huagang, Cai Xinyu, Tan Li, Li Shu, Zhu Junmin, Li Ming, Hu Xiaomei, Zhou Renjie, Rao Xiancai, Yang Yi

Abstract excerpt

Staphylococcus aureus is an important pathogen that produces abundant virulence factors, which cause various diseases that burden human health worldwide. The stress response regulon called sigma factor B (SigB) is a well-characterized global regulator that is involved in the regulation of S. aureus virulence, pigmentation, and biofilm formation. However, the regulatory network upon SigB in S. aureus is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biofilms
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Micrococcal Nuclease

Share to Real-Time Polymerase Chain Reaction

Share to Sigma Factor

Share to Staphylococcal Infections

Share to Staphylococcus aureus

Share to Virulence Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 29691368
DOI: 10.1038/s41426-018-0078-1
PMCID: PMC5915575

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel SigB(Q225P) mutation in Staphylococcus aureus retains virulence but promotes biofilm formation.PMID 29691368Read ↗

The Q225P Mutation in SigB Promotes Membrane Vesicle Formation in Staphylococcus aureus.Semantic proximity Read ↗

Alternative sigma factor B reduces biofilm formation and stress response in milk-derived Staphylococcus aureusSemantic proximity Read ↗

Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections.Semantic proximity Read ↗

Salicylic acid activates sigma factor B by rsbU-dependent and -independent mechanisms.Semantic proximity Read ↗

GlmS plays a key role in the virulence factor expression and biofilm formation ability of Staphylococcus aureus promoted by advanced glycation end productsSemantic proximity Read ↗

Nuclease modulates biofilm formation in community-associated methicillin-resistant Staphylococcus aureus.Semantic proximity Read ↗

Factors Determining Staphylococcus aureus Susceptibility to Photoantimicrobial Chemotherapy: RsbU Activity, Staphyloxanthin Level, and Membrane FluiditySemantic proximity Read ↗

Staphylococcus aureus SOS response: Activation, impact, and drug targetsSemantic proximity Read ↗

Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus.Semantic proximity Read ↗

Exploring Staphylococcus aureus Virulence Factors; Special Emphasis on StaphyloxanthinSemantic proximity Read ↗

SigB Is a Dominant Regulator of Virulence in Staphylococcus aureus Small-Colony VariantsSemantic proximity Read ↗

An insight into the significance of the DnaK heat shock system in Staphylococcus aureus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.