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Article

Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections.

PLoS pathogens - 1 Apr 2015

Tuchscherr Lorena, Bischoff Markus, Lattar Santiago M, Noto Llana Mariangeles, Pförtner Henrike, Niemann Silke, Geraci Jennifer, Van de Vyver Hélène, Fraunholz Martin J, Cheung Ambrose L, Herrmann Mathias, Völker Uwe, Sordelli Daniel O, Peters Georg, Löffler Bettina

Abstract excerpt

Staphylococcus aureus is a major human pathogen that causes a range of infections from acute invasive to chronic and difficult-to-treat. Infection strategies associated with persisting S. aureus infections are bacterial host cell invasion and the bacterial ability to dynamically change phenotypes from the aggressive wild-type to small colony variants (SCVs), which are adapted for intracellular long-term...

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Identifiers

PMID: 25923704
DOI: 10.1371/journal.ppat.1004870
PMCID: PMC4414502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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