Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation.

Infection and immunity - 1 Apr 2009

Lauderdale Katherine J, Boles Blaise R, Cheung Ambrose L, Horswill Alexander R

Abstract excerpt

Staphylococcus aureus is a proficient biofilm former on host tissues and medical implants. We mutagenized S. aureus strain SH1000 to identify loci essential for ica-independent mechanisms of biofilm maturation and identified multiple insertions in the rsbUVW-sigB operon. Following construction and characterization of a sigB deletion, we determined that the biofilm phenotype was due to a lack of sigma factor B...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biofilms
Share to Methicillin-Resistant Staphylococcus aureus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutagenesis, Insertional

Share to N-Acetylmuramoyl-L-alanine Amidase

Share to Peptide Hydrolases

Share to RNA, Bacterial

Share to Sigma Factor

Share to Staphylococcus aureus

Source

Open in PubMed Open full text

Identifiers

PMID: 19188357
DOI: 10.1128/IAI.01036-08
PMCID: PMC2663138

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interconnections between Sigma B, agr, and proteolytic activity in Staphylococcus aureus biofilm maturation.PMID 19188357Read ↗

SigB Is a Dominant Regulator of Virulence in Staphylococcus aureus Small-Colony VariantsSemantic proximity Read ↗

Staphopains modulate Staphylococcus aureus biofilm integrity.Semantic proximity Read ↗

Virulence factors in biofilm formation and therapeutic strategies for Staphylococcus aureus: A reviewSemantic proximity Read ↗

Identification of the sigB operon in Staphylococcus epidermidis: construction and characterization of a sigB deletion mutant.Semantic proximity Read ↗

Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections.Semantic proximity Read ↗

Alternative sigma factor B reduces biofilm formation and stress response in milk-derived Staphylococcus aureusSemantic proximity Read ↗

Essential role for the major autolysin in the fibronectin-binding protein-mediated Staphylococcus aureus biofilm phenotype.Semantic proximity Read ↗

The role of sigmaB in persistence of Staphylococcus epidermidis foreign body infection.Semantic proximity Read ↗

SarA and not σ <sup>B</sup> is essential for biofilm development by <i>Staphylococcus aureus</i>Semantic proximity Read ↗

RsbU-dependent regulation of Staphylococcus epidermidis biofilm formation is mediated via the alternative sigma factor sigmaB by repression of the negative regulator gene icaR.Semantic proximity Read ↗

Regulation of biofilm formation by sigma B is a common mechanism in Staphylococcus epidermidis and is not mediated by transcriptional regulation of sarA.Semantic proximity Read ↗

Population diversification in Staphylococcus aureus biofilms may promote dissemination and persistence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.