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Article

The spen family protein FPA controls alternative cleavage and polyadenylation of RNA.

Developmental cell - 16 Feb 2010

Hornyik Csaba, Terzi Lionel C, Simpson Gordon G

Abstract excerpt

The spen family protein FPA is required for flowering time control and has been implicated in RNA silencing. The mechanism by which FPA carries out these functions is unknown. We report the identification of an activity for FPA in controlling mRNA 3' end formation. We show that FPA functions redundantly with FCA, another RNA binding protein that controls flowering and RNA silencing, to control the expression of...

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Identifiers

PMID: 20079695
DOI: 10.1016/j.devcel.2009.12.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The spen family protein FPA controls alternative cleavage and polyadenylation of RNA.PMID 20079695Read ↗

FY is an RNA 3' end-processing factor that interacts with FCA to control the Arabidopsis floral transition.Semantic proximity Read ↗

Arabidopsis PCFS4, a homologue of yeast polyadenylation factor Pcf11p, regulates FCA alternative processing and promotes flowering time.Semantic proximity Read ↗

Transcription termination and chimeric RNA formation controlled by Arabidopsis thaliana FPA.Semantic proximity Read ↗

An allelic series reveals essential roles for FY in plant development in addition to flowering-time control.Semantic proximity Read ↗

Functional significance of the alternative transcript processing of the Arabidopsis floral promoter FCA.Semantic proximity Read ↗

Widespread role for the flowering-time regulators FCA and FPA in RNA-mediated chromatin silencing.Semantic proximity Read ↗

Integrative genome-wide analysis reveals HLP1, a novel RNA-binding protein, regulates plant flowering by targeting alternative polyadenylation.Semantic proximity Read ↗

The RNA-binding protein FCA and the adaptor protein ECAP coordinately repress FLC to facilitate flowering in Arabidopsis.Semantic proximity Read ↗

FPA, a gene involved in floral induction in Arabidopsis, encodes a protein containing RNA-recognition motifs.Semantic proximity Read ↗

The Arabidopsis RNA-binding protein FCA requires a lysine-specific demethylase 1 homolog to downregulate FLC.Semantic proximity Read ↗

Altered interactions within FY/AtCPSF complexes required for Arabidopsis FCA-mediated chromatin silencing.Semantic proximity Read ↗

Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis.Semantic proximity Read ↗

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