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Article

A viral phospholipase A2 is required for parvovirus infectivity.

Developmental cell - 1 Aug 2001

Zádori Z, Szelei J, Lacoste M C, Li Y, Gariépy S, Raymond P, Allaire M, Nabi I R, Tijssen P

Abstract excerpt

Sequence analysis revealed phospholipase A2 (PLA2) motifs in capsid proteins of parvoviruses. Although PLA2 activity is not known to exist in viruses, putative PLA2s from divergent parvoviruses, human B19, porcine parvovirus, and insect GmDNV (densovirus from Galleria mellonella), can emulate catalytic properties of secreted PLA2. Mutations of critical amino acids strongly reduce both PLA2 activity and,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11702787
DOI: 10.1016/s1534-5807(01)00031-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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