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Article

Safety and immunogenicity of parvovirus B19 virus-like particle vaccine lacking phospholipase A2 activity

14 Sept 2022

Abstract excerpt

Parvovirus B19 (B19) belongs to the Erythroparvovirus genus and is known to cause the fifth disease in children. Primary infection of pregnant women is associated with a high risk of hydrops fetalis and stillbirth due to severe fetal anemia. Virus-like particle (VLP) vaccine candidates for B19 have been developed, although none have been approved so far. The B19 phospholipase A2 domain (B19 PLA2), located in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36114131
DOI: 10.1016/j.vaccine.2022.09.009

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