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Article

VP1u phospholipase activity is critical for infectivity of full-length parvovirus B19 genomic clones.

Virology - 10 May 2008

Filippone Claudia, Zhi Ning, Wong Susan, Lu Jun, Kajigaya Sachiko, Gallinella Giorgio, Kakkola Laura, Söderlund-Venermo Maria, Young Neal S, Brown Kevin E

Abstract excerpt

Three full-length genomic clones (pB19-M20, pB19-FL and pB19-HG1) of parvovirus B19 were produced in different laboratories. pB19-M20 was shown to produce infectious virus. To determine the differences in infectivity, all three plasmids were tested by transfection and infection assays. All three clones were similar in viral DNA replication, RNA transcription, and viral capsid protein production. However, only...

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Share to Amino Acid Sequence
Share to Capsid Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cloning, Molecular

Share to Genome, Viral

Share to Parvovirus B19, Human

Share to Phospholipases A2

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 18252260
DOI: 10.1016/j.virol.2008.01.002
PMCID: PMC4283219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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