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Article

Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice.

Developmental cell - 1 Aug 2001

Tay J, Richter J D

Abstract excerpt

CPEB is a sequence-specific RNA binding protein that regulates translation during vertebrate oocyte maturation. Adult female CPEB knockout mice contained vestigial ovaries that were devoid of oocytes; ovaries from mid-gestation embryos contained oocytes that were arrested at the pachytene stage. Male CPEB null mice also contained germ cells arrested at pachytene. The germ cells from the knockout mice harbored...

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Source

Identifiers

PMID: 11702780
DOI: 10.1016/s1534-5807(01)00025-9

Genes

CPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice.PMID 11702780Read ↗

CPEB controls oocyte growth and follicle development in the mouseSemantic proximity Read ↗

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CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency.Semantic proximity Read ↗

Embryonic poly(A)-binding protein is required at the preantral stage of mouse folliculogenesis for oocyte–somatic communication†Semantic proximity Read ↗

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